Students

Rohit Kumar Jangra

Major: Virology

Mentor: Dr. Stanley M. Lemon

Publications/Experience:
Jangra RK, Tosh C, Sanyal A, Hemadri D, Bandyopadhyay SK. (2005). Antigenic and genetic analyses of foot-and-mouth disease virus type A isolates for selection of candidate vaccine strain reveals emergence of a variant virus that is responsible for most recent outbreaks in India. Virus Research. 112(1-2): 52-59.

Research Description:
Nearly 3% of the world population is infected with hepatitis C virus (HCV) that causes persistent infections in humans leading to chronic hepatitis, cirrhosis and hepatocellular carcinoma. HCV is an enveloped hepatotropic virus carrying a ~9.6 Kb-long single-stranded positive sense RNA genome. MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs (~23 nts in length) that regulate posttranscriptional gene expression by targeting complementary sequences in mRNAs for RNA degradation and/or translational blockade. miRNAs regulate a multitude of physiological and pathological processes ranging from growth and development to oncogenesis and antiviral defense. Recently, it was reported that hepatitis C virus (HCV) utilizes one of the liver-specific miRNA viz. miR-122 for facilitating its RNA replication via specific interactions with highly conserved sequences in HCV 5’NTR. My research is focused on delineating the mechanistic details of role of miR-122 in HCV RNA replication.

Hometown: Hisar (Haryana), INDIA
Education: BS (BVSc & AH) CCS Haryana Agricultural University, Hisar, Haryana INDIA
MS (MVSc( Indian Veterinary Institute (IVRI) Izatnagar, Bareillym UP INDIA
Contact: rkjangra@utmb.edu

« Back to the Student Page

• UTMB Home Page
• Graduate Program
• Student Research Seminars
• Graduate Student Organization
• Office of Student Life
• Committee for Career Development